PD09 A prospective study of outcomes of narrowband ultraviolet B for the treatment of paediatric atopic dermatitis, with additional breakdown by ethnicity/skin type

Abstract Narrowband UVB (NBUVB) phototherapy is regarded as a second-line treatment for atopic dermatitis (AD) when response to first-line ineffective. We undertook prospective study evaluating NBUVB in paediatric AD assess changes pretreatment Eczema Area and Severity Index (EASI) score immediately postphototherapy 12 months later. subanalysed different skin types. All patients had three times weekly up maximum of 40 exposures. Follow-up was every 3 1 year postphototherapy. In total, 58 were recruited [37 (64%) men, 21 (36%) women, mean age 10.6 years (range 4.1–16.9 years)]. Skin types/ethnicity follows: White, n = 22 (38%); South Asian (Pakistani/Indian/Bangladeshi), 17 (29%); Black African/Caribbean, 9 (16%); other, 10 (17%). The immediate post-treatment EASI reductions vs. baseline scores 10.0 (entire cohort), 12.4 (White), 8.6 (South Asian), 2.5 (Black African/Caribbean) 7.5 (other). A ≥ 75% increase (EASI 75) achieved the 49% entire cohort, 48% White people, 50% Asians, 44% African/Caribbean people 56% others. 90% 90) 15% whole group, 14% 13% 22% 11% At post-treatment, reduction 7.6 9.0 −2.1 (i.e. worsening) 8.0 75 28% 33% 40% For those who responded, there similar proportion achieving across However, more variation with colour. acknowledge that existing scoring systems may lead underscoring severity erythema therefore overall darker Although highest group patients, higher Black/Caribbean 90 at end treatment; however, number this small. Our showed sustained after stopping treatment. greater risk relapse.